01853nas a2200349   4500000000100000008004100001260001300042653001500055653001000070653000900080653002900089653001700118653001100135653001200146653002400158653001600182653001000198653001700208653002800225100001900253700001300272700001400285700001800299700001300317700001000330245007200340856008400412300000900496490000700505520097700512022001401489       1991                            d  c1991 Jan10aAdolescent10aAdult10aAged10aDermatitis Herpetiformis10aEye diseases10aHumans10aleprosy10aLeprosy, Borderline10aMiddle Aged10aPupil10aTime Factors10aTuberculosis, Pulmonary1 aKaraçorlu M A1 aSürel Z1 aCakiner T1 aHanyaloğlu E1 aSaylan T1 aMat C00aPupil cycle time and early autonomic involvement in ocular leprosy.  uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC504106/pdf/brjopthal00061-0052.pdf  a45-80 v753 a<p>Ocular complications of leprosy patients often develop insidiously and with few if any symptoms. This study involves measurement of the pupil cycle time (PCT) to evaluate the autonomic nerve system of the iris to determine the presence of subclinical intraocular involvement. The study included 19 lepromatous (LL), 19 borderline lepromatous (BL), and five borderline tuberculoid (BT) leprosy patients and involved 25 healthy volunteers, 10 patients with pulmonary tuberculosis and eight with Duhring disease. The PCT was measured in these groups. In all leprosy groups included in the study the PCT was higher than in the control groups. Moreover, the PCT of the leprosy patients without any intraocular involvement was higher than in the controls. These results show that in the ophthalmic examination of leprosy patients without any symptoms the fact that autonomic nerve system of the eye is affected by the leprosy can often be determined by measuring the PCT.</p>  a0007-1161