02157nas a2200433 4500000000100000008004100001260000900042653001500051653001000066653000900076653002600085653002400111653001000135653002500145653001800170653001600188653001100204653001600215653002100231653001200252653001600264653002500280653003100305653000900336653001600345100001100361700002500372700001200397700002000409700001200429700001500441700002200456700001900478245006600497300000900563490001500572520112200587022001401709 2008 d c200810aAdolescent10aAdult10aAged10aAntibodies, Bacterial10aAntigens, Bacterial10aChild10aConfidence Intervals10aCytodiagnosis10aGlycolipids10aHumans10aImmunoassay10aImmunoglobulin M10aleprosy10aMiddle Aged10aMycobacterium leprae10aReproducibility of Results10aSkin10aYoung Adult1 aLyon S1 aCastorina da Silva R1 aLyon AC1 aFaria Grossi MA1 aLyon SH1 aAzevedo ML1 aBührer-Sékula S1 aCosta Rocha MO00aAssociation of the ML Flow serologic test to slit skin smear. a23-60 v41 Suppl 23 a

A descriptive, exploratory study was conducted analyzing the association of covariables in the results of the ML Flow serological test and slit skin smear. A total of 60 leprosy cases diagnosed at the state Sanitary Dermatology Referral Center were investigated. Slit skin smear samples were collected from four sites and the results were expressed by the bacillary index. ML Flow was registered in both qualitative and semi-quantitative terms. Cohen's kappa coefficient was used to study the agreement with Landis and Koch's observer criteria for interpretation. For statistical analysis, the logistic regression model and Kruskal-Wallis test were used. ML Flow showed a strong association with slit skin smear results, since a gradual increase in BI was accompanied by a semi-quantitative rise in antibody levels measured by ML Flow, with 100% positivity in cases presenting a positive slit skin smear. Given its strong correlation to slit skin smear, the results of this study provide evidence that the ML Flow test could be a valuable auxiliary tool in the classification and treatment of leprosy patients.

 a1678-9849