01286nas a2200229   4500000000100000008004100001260001300042653004400055653002900099653001600128653001100144653002300155653001800178100001600196700001200212700002000224245003900244300001100283490000600294520074200300022001401042       2009                            d  c2009 Sep10aAnti-Inflammatory Agents, Non-Steroidal10aClinical Trials as Topic10aClofazimine10aHumans10aLeprostatic Agents10aSkin Diseases1 aGurfinkel P1 aPina JC1 aRamos-E-Silva M00aUse of clofazimine in dermatology.  a846-510 v83 a<p>Clofazimine is the riminophenazine dye that, due to its antibacterial and anti-inflammatory properties, has been used for several diseases. This article reviews all major characteristics and uses relating to clofazimine, from its pharmacology to its indications in several skin diseases, over and above its classical and well established use in the treatment of leprosy. Due to its anti-inflammatory and antimicrobial properties, clofazimine has a wide spectrum for application in dermatology. The indications include neutrophilic, granulomatous and infectious diseases. Although it is not the first-choice medication in most of the cases, clofazimine should always be considered among the therapeutic options in refractory cases.</p>  a1545-9616