01126nas a2200229 4500000000100000008004100001260001300042653001200055653003000067653001800097653001100115653001200126653001500138100001800153700001500171700001500186245003100201300001200232490000700244520063100251022001400882 1991 d c1991 Aug10aAnimals10aEye Infections, Bacterial10aGlobal health10aHumans10aleprosy10aPrevalence1 aJohnstone P A1 aGeorge A D1 aMeyers W M00aOcular lesions in leprosy. a297-3030 v233 a

Leprosy is the world's third leading cause of blindness. Mechanisms of ocular infection include direct or hematogenous invasion of the globe, or involvement of branches of the facial or corneal nerves, contributing to exposure keratitis. Lesions of ocular leprosy can be classified as potentially sight threatening or academic. A review of the world's literature showed no geographic or climactic trends in disease course. Leprosy in humans is contrasted with experimental disease in animal models; early experimental disease may be primarily neurally mediated rather than hematogenously mediated as previously thought.

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