01465nas a2200301   4500000000100000008004100001260001300042653001000055653001100065653001100076653002300087653001200110653002100122653002200143653001700165653003100182653001600213653000900229653003200238100001100270700001400281700001200295245006900307300001100376490000700387520075500394022001401149       2009                            d  c2009 Jun10aAdult10aFemale10aHumans10aLeprostatic Agents10aleprosy10aNasal Cartilages10aNasal Obstruction10aNasal Septum10aNose Deformities, Acquired10aRhinoplasty10aRibs10aTransplantation, Autologous1 aShah A1 aZeitler D1 aWise JB00aNasal reconstruction of the leprosy nose using costal cartilage.  a547-550 v423 a<p>Leprosy is a chronic granulomatous infection of the skin and peripheral nerves that often leads to gross deformation of the nasal skeleton and subsequent formation of a saddle-nose deformity. Reconstruction of the nose following Mycobacterium leprae infection has challenged surgeons for centuries. As a result, a number of different techniques have been attempted with varying outcomes. This article describes the case and surgical treatment of a 37-year old female who presented with a subtotal nasoseptal perforation and saddle-nose deformity secondary to previous infection with leprosy. Reconstruction was achieved via an open septorhinoplasty approach using autologous costal cartilage grafts, yielding a successful postoperative result.</p>  a1557-8259