01210nas a2200241   4500000000100000008004100001260001300042653001800055653001600073653001100089653002300100653001200123653000900135100001400144700001700158700001200175700001300187245008900200300001100289490000700300520064700307022001400954       2009                            d  c2009 Jun10aGlobal health10aHistiocytes10aHumans10aLeprostatic Agents10aleprosy10aSkin1 aSehgal VN1 aSrivastava G1 aSingh N1 aPrasad P00aHistoid leprosy: the impact of the entity on the postglobal leprosy elimination era.  a603-100 v483 a<p>A fresh focus on histoid leprosy is the primary objective of this article, especially in the context of the postglobal leprosy elimination era. The emergence of the entity following dapsone monotherapy is well recognized, in addition to de novo cases. Irregular and inadequate therapies, coupled with resistance to dapsone and/or mutant organisms, are responsible. It was considered to be worthwhile to take stock of the condition through its history, nomenclature, epidemiology, clinical characteristics, diagnosis, and differential diagnosis. The bacteriologic and histopathologic features and immunologic profile are also described.</p>  a1365-4632