01152nas a2200253   4500000000100000008004100001260001300042653002100055653001100076653001200087653002500099653002500124653000900149653002500158653001800183100001200201700001500213245004500228300001100273490000700284050001200291520058100303022001400884       1991                            d  c1991 Sep10aErythema Nodosum10aHumans10aleprosy10aLeprosy, lepromatous10aLeprosy, Tuberculoid10aSkin10aT-Lymphocyte Subsets10aT-Lymphocytes1 aRea T H1 aModlin R L00aImmunopathology of leprosy skin lesions.  a188-930 v10  aREA19913 a<p>These immunopathogenesis studies of leprosy have provided new insight into the immune response to M leprae at the site of disease activity, the skin lesions. The study of leprosy provides a model for studying the immune response to foreign pathogens as well as the immunopathologic study of skin lesions. Further developments in immunology and molecular biology will increase our ability to dissect such immune mechanisms. For example, the advent of the polymerase chain reaction will allow for a more complete elucidation of the cytokines in inflammatory skin lesions.</p>  a0278-145X