01722nas a2200277   4500000000100000008004100001260001700042653001000059653002800069653001100097653001100108653002300119653001200142653002300154653002500177653002500202100001400227700002400241700001200265700001100277245006600288300001000354490000700364520105900371022001401430       2009                            d  c2009 Mar-Apr10aAdult10aDiagnosis, Differential10aFemale10aHumans10aLeprostatic Agents10aleprosy10aLymphatic Diseases10aLymphoma, Follicular10aSecondary Prevention1 aKiran K U1 aKrishna Moorthy K V1 aMeher V1 aRao NP00aRelapse of leprosy presenting as nodular lymph node swelling.  a177-90 v753 a<p>Lymphadenopathy is known to be associated with lepromatous leprosy and has also been observed as a feature of type-2 lepra reaction. However, nodular lymph node enlargement is not commonly reported in leprosy patients or as a feature of relapse. We herewith are presenting a case of bacteriological relapse in a patient of lepromatous leprosy treated 22 years before till smear negativity with WHO multidrug therapy (MDT) multibacillary type (MB). She presented with prominent nodular swelling of the cervical group of lymph nodes along with generalized lymphadenopathy, which was mistakenly treated as tubercular lymphadenopathy. A diagnosis of late bacteriological relapse of lepromatous leprosy presenting with prominent lymphadenopathy and ENL was made after relevant investigations. The patient was started on treatment with WHO MDT MB (daily dapsone and clofazimine and monthly rifampicin) and thalidomide (200 mg/day). Nerve pain regressed within 2 weeks of therapy. The lymph nodal swelling regressed within 3 months of starting treatment.</p>  a0973-3922