01362nas a2200277 4500000000100000008004100001260001300042653001000055653002700065653001600092653001900108653001100127653004800138653001200186653000900198100001100207700001400218700001200232700001400244700001100258245007200269300000900341490000700350520071300357022001401070 2009 d c2009 Mar10aAdult10aAnti-Retroviral Agents10aComorbidity10aHIV Infections10aHumans10aImmune Reconstitution Inflammatory Syndrome10aleprosy10aMale1 aChow D1 aOkinaka L1 aSouza S1 aShikuma C1 aTice A00aHansen's disease with HIV: a case of immune reconstitution disease. a27-90 v683 a

Immune reconstitution inflammatory syndrome (IRIS) is an acute symptomatic expression of a latent infection during the recovery of the immune system usually as a response to antiretroviral therapy (ART). Opportunistic infections can trigger IRIS. Hansen's disease is an infection caused by Mycobacterium leprae (M. leprae). There have been a limited number of case reports reporting the presentation of the co-infection of HIV and M. leprae. We report an unique case of IRIS in a patient co-infected with HIV and M. leprae presenting as an exacerbation of his Hansen's Disease where the patient's skin lesions progressed from borderline tuberculoid to lepromatous leprosy following ART administration.

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