01862nas a2200277   4500000000100000008004100001260001300042653001000055653000900065653002200074653003000096653002200126653001100148653001200159653001600171653001600187653001800203100001400221700001400235245008800249856004100337300001000378490000700388520117500395022001401570       1991                            d  c1991 Sep10aAdult10aAged10aAged, 80 and over10aEye Infections, Bacterial10aFollow-Up Studies10aHumans10aleprosy10aMiddle Aged10aNetherlands10aVisual Acuity1 aHogeweg M1 aFaber W R00aProgression of eye lesions in leprosy: ten-year follow-up study in The Netherlands.  uhttp://ila.ilsl.br/pdfs/v59n3a02.pdf  a392-70 v593 a<p>Forty-eight leprosy patients in The Netherlands were re-examined 10 years after initial examination. Forty-six of these patients had received a course of multidrug therapy (MDT), according to the World Health Organization recommendation, at the time of their initial examination. Two patients had burned-out disease and had been merely under observation. Out of 40 patients, who initially did not show eye complications due to leprosy, 37 patients were essentially the same 10 years later. The eyes had changed in 3 multibacillary patients: 1 patient had developed a late type 1 reaction with facial nerve involvement and lagophthalmos; 2 patients had undergone intra-ocular surgery for cataract and acute glaucoma, respectively. Out of 8 patients with pre-existing eye involvement, 1 patient recovered and the lesions in 2 patients remained unaltered. One patient showed progression of pre-existing exposure keratitis. Four patients had undergone cataract extractions; all four patients were lepromatous, with a long history of disease and signs of iris involvement at the first examination. The main progressive lesions were cataracts in lepromatous patients.</p>
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