01341nas a2200325   4500000000100000008004100001260001300042653001500055653001000070653000900080653002200089653001000111653001200121653001100133653001100144653001200155653000900167653001600176653002300192653003000215653002400245100001400269700001400283700001400297245006600311300001000377490000700387520060700394022001401001       1989                            d  c1989 Apr10aAdolescent10aAdult10aAged10aAged, 80 and over10aChild10aDapsone10aFemale10aHumans10aleprosy10aMale10aMiddle Aged10aPatient Compliance10aPredictive Value of Tests10aSelf Administration1 aRoche P W1 aFailbus S1 aBritton W00aSelf-administered drug compliance in Nepali leprosy patients.  a59-610 v193 a<p>The self administration of dapsone by Nepali leprosy patients receiving multidrug therapy was assessed by a colorimetric and a filter paper spot test. Overall 45 out of 337 (13.3%) patients were found to be non-compliant. The relation of non-compliance to sex, age, leprosy classification, therapy type and length of therapy was investigated. The spot test was compared with the colorimetric assay and found to have a relative sensitivity of 99.3% and specificity of 95.4%. Follow up of patients was successful in that two-thirds of non-compliant patients were compliant on their follow-up test.</p>  a0049-4755