01952nas a2200373 4500000000100000008004100001260001300042653001500055653001000070653000900080653002200089653001200111653001500123653002500138653001100163653001100174653001200185653000900197653001600206653003100222653001800253653001300271100001300284700001300297700001500310700001100325700001400336700001600350245006600366300001000432490000700442520111500449022001401564 2008 d c2008 Jun10aAdolescent10aAdult10aAged10aAged, 80 and over10aAnimals10aArmadillos10aCase-Control Studies10aFemale10aHumans10aleprosy10aMale10aMiddle Aged10aSurveys and Questionnaires10aUnited States10aZoonoses1 aClark BM1 aMurray C1 aHorvath LL1 aDeye G1 aRasnake M1 aLongfield R00aCase-control study of armadillo contact and Hansen's disease. a962-70 v783 a

Hansen's disease (HD) continues to have worldwide impact despite efforts to eradicate the disease. Although a definitive transmission mode has not been identified, data supports an association between HD and contact with the nine-banded armadillo. We conducted a case-control study of 28 HD patients to determine if there is an association between armadillo exposure and HD. There was no association between HD and place of birth or having hunted, consumed, or had direct or indirect contact with deer, birds, or squirrels. Univariate analysis showed that residence in Mexico (P = 0.001), hunting rabbits (P = 0.04), cleaning rabbits (P < 0.001), and armadillo exposure from hunting (P = 0.005), cleaning (P = 0.004), consuming (P = 0.002) them, or having direct armadillo contact (P = 0.017) were associated with HD. Multivariate analysis showed that eating armadillos (P = 0.039, odds ratio [OR] = 3.65, 95% confidence interval [CI] = 1.07-12.4), cleaning rabbits (P = 0.018, OR = 4.08, 95% CI = 1.27-13.1), and having lived in Mexico (P = 0.006, OR = 24.9, 95% CI = 2.52-245) were associated with HD.

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