01123nas a2200337 4500000000100000008004100001260001300042653002000055653001100075653001200086653001600098653002700114653002500141653001500166653002400181653000900205653002500214100001500239700001300254700001600267700001400283700000900297700001200306700001600318700001200334245012400346300001000470490000700480520028400487022001400771 2008 d c2008 Feb10aCells, Cultured10aHumans10aleprosy10aMacrophages10aMicrofilament Proteins10aMycobacterium leprae10aPhagosomes10aSignal Transduction10aSkin10aToll-Like Receptor 21 aTanigawa K1 aSuzuki K1 aKawashima A1 aMishima M1 aWu H1 aAkama T1 aTakeshita F1 aIshii N00a[Molecular mechanisms for intracellular parasitisation and exclusion in macrophage infected with Mycobacterium leprae]. a57-610 v773 a

It was previously demonstrated that TLR2 and CORO1A (TACO, Coronin 1, p57) localize phagosome membrane of macrophage. However, the functional relationship between TLR2 and CORO1A was not known. We show here that there is a functional counteraction between TLR2 and CORO1A.

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