02143nas a2200349   4500000000100000008004100001260001700042653001500059653001000074653001600084653000900100653001000109653002100119653001100140653001100151653002100162653001200183653001600195100002000211700001500231700001400246700001400260700001400274700001200288700001300300700001300313245014200326300001000468490000700478520129400485022001401779       2006                            d  c2006 Jul-Dec10aAdolescent10aAdult10aAge Factors10aAged10aChild10aChild, Preschool10aFamily10aHumans10aInterferon-gamma10aleprosy10aMiddle Aged1 aGüdücüoglu H1 aBerktaş M1 aBozkurt H1 aAkdeniz N1 aKutluay N1 aYaman G1 aBayram Y1 aAndiç S00aEvaluation of related with age of IFN-gamma levels of treated leprosy patients and their healthy relatives compared with a control group.  a105-80 v653 a<p><b>OBJECTIVE: </b>This study was to search how change with age of IFN-gamma (IFN-gamma) levels of leprosy patients who had received or still undergoing treatment, their healthy close relatives and healthy people.</p><p><b>METHOD: </b>From a total of 39 patients, 28 had received leprosy treatment and recovered with some defects [17 Lepromatous Leprosy(LL), 7 Borderline Lepromatous (BL), 3 Borderlien Tuberculoid (BT), 1 Tuberculoid form (TT)] and 11 (9 LL, 2 BL) were undergoing therapy in a hospital at that moment. Close relatives of the patients included 39 people living with treated patients in the same house and the control group consisted of 39 healthy people. Human IFN-gamma kits were used as a solid phase sandwich ELISA method.</p><p><b>RESULTS: </b>The IFN-gamma values of treated leprosy patients, therapy receiving patients, relatives group's and control group's were detected as 11-20 pg/mL, 11-18 pg/mL, 12-145 pg/mL and 12-65 pg/mL respectively.</p><p><b>CONCLUSION: </b>According to the statistical evaluation of these three groups, IFN-gamma levels of patients were detected lower than other two groups. According to the age, if IFN-gamma levels were compared, it was detected that significant relationship between relatives groups and interferon gamma levels.</p>  a1222-3891