01199nas a2200241 4500000000100000008004100001260000900042653001800051653002100069653003200090653001100122653001200133653001600145653003400161653003000195100001500225700002100240245006800261300000900329490000700338520059800345022001400943 1991 d c199110aB-Lymphocytes10aCarboxylesterase10aCarboxylic Ester Hydrolases10aHumans10aleprosy10aLymphocytes10aT-Lymphocytes, Helper-Inducer10aT-Lymphocytes, Regulatory1 aMacedo H W1 aQuirico-Santos T00aNonspecific esterase staining of lymphocyte subsets in leprosy. a50-20 v413 a

A comparative study of lymphocyte subpopulations from leprosy patients were carried out using nonspecific esterase (ANAE) staining and monoclonal antibodies. Regardless of the methodology used, an intense reduction in the total number of the T helper/inducer subset and an inversion of the helper/suppressor ration could be observed. These alterations were more evident with the progress of the disease from the tuberculoid (TL) to the lepromatous (LL) pole. Thus ANAE may be considered an economical and reliable method to be used in the study of the immune status of leprosy patients.

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