02235nas a2200349 4500000000100000008004100001260001300042653001000055653000900065653001100074653001100085653001200096653000900108653002100117653001600138653003000154653003700184653001400221653003200235653003100267653001100298100001400309700001400323700001400337245013600351856005100487300001100538490000700549050003200556520128300588022001401871 2007 d c2007 Sep10aAdult10aAged10aFemale10aHumans10aleprosy10aMale10aMental Disorders10aMiddle Aged10aPredictive Value of Tests10aPsychiatric Status Rating Scales10aROC Curve10aSensitivity and Specificity10aSurveys and Questionnaires10aTurkey1 aSenturk V1 aStewart R1 aSagduyu A00aScreening for mental disorders in leprosy patients: comparing the internal consistency and screening properties of HADS and GHQ-12. uhttps://leprosyreview.org/article/78/3/23-1242 a231-420 v78 aInfolep Library - available3 a

OBJECTIVE: The aim of the study was to investigate the internal consistency and screening properties of the General Health Questionnaire-12 (GHQ-12) and the Hospital Anxiety and Depression Scale (HADS) in Turkish patients with leprosy.

METHODS: The two screening instruments and a fully structured diagnostic interview (CIDI) were administered to 65 people drawn from all leprosy inpatient units in Turkey between March and June of 2001. The scales were evaluated using Cronbach's alpha and Receiver Operating Characteristics (ROC) analyses. For each scale, criterion validity was assessed for any psychiatric disorder, depressive disorder and anxiety disorder.

RESULTS: The Cronbach alpha coefficients for the GHQ-12 and HADS were 0.84 and 0.81 respectively. For detecting any psychiatric disorder, the optimal cut-off for the GHQ-12 was 4/5 (sensitivity 0.82, specificity 0.62). The optimal cut-off for the HADS total score was 12/13 (sensitivity 0.80, specificity 0.77).

CONCLUSION: The results indicate that the General Health Questionnaire-12 and Hospital Anxiety and Depression Scale have satisfactory internal consistency, and performed well to a similar extent for detecting psychiatric disorders in leprosy patients.

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