01213nas a2200277   4500000000100000008004100001260001300042653001000055653000900065653001100074653000900085653001100094653001400105653001200119653000900131653001600140653001600156653002300172100001400195700001500209245004500224300001000269490000700279520063500286022001400921       1991                            d  c1991 Sep10aAdult10aAged10aFemale10aHand10aHumans10aIncidence10aleprosy10aMale10aMiddle Aged10aRadiography10aRheumatic Diseases1 aPaira S O1 aRoverano S00aThe rheumatic manifestations of leprosy.  a274-60 v103 a<p>We investigated the rheumatic and laboratory features in 25 patients with Hansen's disease. Sixteen (64%) developed a broad range of rheumatic manifestations, the most common being a distinctive syndrome of swollen hands observed in 10 patients (66.5%). These manifestations were more frequent in patients with lepromatous leprosy. There was no correlation between articular clinical findings and X-ray or laboratory abnormalities. A careful clinical history and the recognition of rheumatic features will help to differentiate patients with leprosy and rheumatic manifestations from those with a primary rheumatic disease.</p>  a0770-3198