02979nas a2200433 4500000000100000008004100001260001300042653001500055653001000070653001000080653002100090653001900111653001100130653002100141653001100162653001100173653002000184653002300204653001200227653000900239653001900248653001600267653001500283653003700298653002600335653002200361100001200383700002000395700001600415700001200431700001200443245016700455856005100622300001100673490000700684050003200691520180800723022001402531 2003 d c2003 Sep10aAdolescent10aAdult10aChild10aChild, Preschool10aCohort Studies10aFemale10aHealth Promotion10aHumans10aInfant10aInfant, Newborn10aLeprostatic Agents10aleprosy10aMale10aMass Screening10aMiddle Aged10aMozambique10aOutcome Assessment (Health Care)10aRetrospective Studies10aTreatment Outcome1 aPhaff C1 aVan Den Broek J1 aMacArthur A1 aNdeve A1 aStuip Y00aCharacteristics and treatment outcomes of leprosy patients detected during a leprosy elimination campaign in Mozambique compared with routinely detected patients. uhttps://leprosyreview.org/article/74/3/22-9239 a229-390 v74 aInfolep Library - available3 a

The objective of this study is to assess whether the case-finding method is a determinant for diagnostic characteristics and treatment outcome of newly diagnosed leprosy patients in Northern Mozambique. This is a retrospective cohort study of 3202 patients on the differences between entrance characteristics and treatment outcome in self-reporting patients and patients detected during a leprosy elimination campaign (LEC) in 1999 in Northern Mozambique. As a consequence of LEC activities, 3 times more patients were found compared with the same period 1 year earlier. After the LEC, case detection remained higher in the years 2000-2002 compared with the years preceding the LEC. More young (<15 years) paucibacillary (PB) cases were diagnosed during LEC activities with, surprisingly, equal percentage of disability grades. No gender imbalance was found in diagnosed LEC patients contrary to self-reporting patient groups. Comparing patients detected during a LEC in 1999 with the passive group of 1998 and 1999 showed a slight but statistically significant better treatment result for the passive group. The classification of leprosy (in favour of PB) and age (in favour of older age groups) were also determinants for favourable treatment outcomes. Volunteers had a significantly better result of treatment compared with trained nurses and regardless of detection method. LEC proved to be a useful addition to the National Leprosy and Tuberculosis Programme in Northern Mozambique. As a result, many new cases were diagnosed and put on treatment and their treatment results were very satisfactory. LEC had a lasting impact on case finding. Volunteers make a valuable contribution to leprosy control in Mozambique because they have consistently better treatment results compared with nurses.

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