01913nas a2200301 4500000000100000008004100001260000900042653001500051653001000066653000900076653001700085653001100102653001100113653001200124653001500136653000900151653001600160653001400176100003200190700002000222700002100242245009500263300001100358490000600369050002400375520119800399022001401597 1980 d c198010aAdolescent10aAdult10aAged10aEye diseases10aFemale10aHumans10aleprosy10aMadagascar10aMale10aMiddle Aged10aPrognosis1 aAndriantsoa-Rasoavelonoro V1 aAndrianjatovo J1 aRazafintsalama C00a[Contribution to investigation of leprosy ocular disease in madagascar (author's transl)]. a469-720 v3 aANDRIANTSOARASO19803 a

250 leprous from National Leprosery of Manankavaly (distant of 30 km from Tananarive) were examined. Among them, 31 patients present ocular disease which occur with that of leper isn't accurately known. Conjuntival reactions as prickling, watering of the eyes with inability to assimilate wind light constitute initial symptoms. Cataract is exceptional (only one case); but we point out; first the superiority of "uveal tractus" disease with 32% of rate; then, the frequency of deep of interstitial keratitis (35%). These lesions are and seem to evolute freely in spite of Iper therapeutic and its stabilisation. So cured of leprosy patients two sided may come back because of the increasing of their ocular sickness. Due to lesion of anterior segment, eye fundus is difficult to analyse, but nervous disease may exist on optical papilla, considering the disproportion between the degrees of uveitis and sight alteration. Researching hansen Bacillus and other germs responsible of eye lesions, we sampled secretions of conjonctiva. We haven't anatome-pathological results because of failure of enucleated eye-ball. Leprosy ocular disease invariably end in blindness by eye-ball atrophy.

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