02103nas a2200433   4500000000100000008004100001260001700042653001500059653001000074653000900084653000900093653002200102653001200124653001500136653002500151653001600176653001800192653001100210653001000221653002000231653001100251653001200262653000900274653001600283653001600299653003000315100001400345700001200359700001600371700001400387700001200401700001500413245011300428300001000541490000700551050001500558520108200573022001401655       2006                            d  c2006 Nov-Dec10aAdolescent10aAdult10aAgar10aAged10aAged, 80 and over10aCandida10aCaregivers10aCase-Control Studies10aConjunctiva10aCulture Media10aFemale10aFungi10aHospitalization10aHumans10aleprosy10aMale10aMiddle Aged10aPenicillium10aStatistics, Nonparametric1 aSantos PM1 aMelo CM1 aMartins SAR1 aChaves AA1 aSá DSP1 aSantos RCR00a[Study of ocular fungal microbiota in patients with Hansen's disease and in individuals who deal with them].  a915-80 v69  aSANTOS20063 a<p><b>PURPOSE: </b>To study the conjunctival fungal flora of patients with leprosy who live in the colony hospital and of those who deal with "Hansen" patients.</p><p><b>METHODS: </b>Sixty-one eyes (61 patients) with Hansen's disease and twenty-five healthy eyes (25 individuals) of individuals who deal with patients were investigated.</p><p><b>RESULTS: </b>Conjunctival fungi growth occurred in 19.67% and 20% of the patients and healthy individuals, respectively. There was no significant difference (p<0.05) regarding fungi percentage of fungi isolated from the conjunctiva between both groups. Candida ssp was the most frequent fungus isolated from the conjunctiva of patients with Hansen's disease, whereas Penicillium spp was the most frequent fungus isolated from the group of people who deal with these patients.</p><p><b>CONCLUSION: </b>The most frequent yeast isolated from conjunctival samples of leprosy patients was Candida, which could be explained by cellular immunodeficiency of these patients, associated with dry eye and the prolonged use of antibiotics.</p>  a0004-2749