01239nas a2200349   4500000000100000008004100001260001300042653001500055653001200070653002600082653001800108653002100126653001100147653002100158653001200179653001400191653000900205653001700214653002500231653002000256653001900276653001500295100000900310700001600319700001400335700001400349245011400363300001200477490000700489520037900496022001400875       2006                            d  c2006 Apr10aAcetamides10aAnimals10aAnti-Infective Agents10aAza Compounds10aDiarylquinolines10aFemale10aFluoroquinolones10aleprosy10aLinezolid10aMice10aMoxifloxacin10aMycobacterium leprae10aNitroimidazoles10aOxazolidinones10aQuinolines1 aJi B1 aChauffour A1 aAndries K1 aJarlier V00aBactericidal activities of R207910 and other newer antimicrobial agents against Mycobacterium leprae in mice.  a1558-600 v503 a<p>As measured by a proportional bactericidal technique in the mouse footpad system, the bactericidal activity against Mycobacterium leprae of R207910 was equal to that of rifapentine, rifampin, or moxifloxacin and significantly greater than those of minocycline, PA-824, and linezolid. These data suggest that R207910 may play an important role in treatment of leprosy.</p>  a0066-4804