01609nas a2200325   4500000000100000008004100001260001300042653002600055653002400081653001100105653002100116653001200137653002400149653001700173100001900190700001400209700001500223700001400238700001300252700001600265700001500281700001700296700001300313245012500326856007800451300001200529490000700541520072100548022001401269       1992                            d  c1992 Jun10aAntibodies, Bacterial10aAntigens, Bacterial10aHumans10aImmunoglobulin G10aleprosy10aMycobacterium bovis10aTuberculosis1 aVan Vooren J P1 aDrowart A1 aDe Bruyn J1 aLaunois P1 aMillan J1 aDelaporte E1 aDeveloux M1 aYernault J C1 aHuygen K00aHumoral responses against the 85A and 85B antigens of Mycobacterium bovis BCG in patients with leprosy and tuberculosis.  uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC265344/pdf/jcm00030-0262.pdf  a1608-100 v303 a<p>Immunoglobulin G antibodies against the 85A and 85B components of the Mycobacterium bovis BCG antigen 85 complex separated by isoelectric focusing were investigated in serum samples from 129 patients representing the major forms of leprosy, 111 tuberculous patients, and 153 healthy subjects. For both of the antigens, a higher degree of staining was observed for lepromatous leprosy patients and patients with active tuberculosis than for the other groups. Because sera from some healthy subjects recognized the 85A antigen, we suggest that antigen 85B is the most useful component of the antigen 85 complex for the serodiagnosis of the multibacillary forms of leprosy or of the active forms of tuberculosis.</p>  a0095-1137