01764nas a2200349 4500000000100000008004100001260001700042653001500059653001000074653001600084653001000100653002100110653001100131653001100142653001000153653001100163653001200174653000900186653001400195653001500209653002600224653001600250653001700266100001300283700001200296245010600308300001100414490000700425050003200432520093600464022001401400 1992 d c1992 Apr-Jun10aAdolescent10aAdult10aAge Factors10aChild10aChild, Preschool10aFemale10aHumans10aIndia10aInfant10aleprosy10aMale10aPregnancy10aRecurrence10aRetrospective Studies10aSex Factors10aUrban Health1 aSaha S P1 aDas K K00aStudy of the characteristics and causes of relapse amongst leprosy cases in an urban area (Calcutta). a169-780 v64 aInfolep Library - available3 a

In this retrospective study of the 3737 cases of leprosy released from treatment and followed-up during 1975 to 1990, 63 had relapsed giving an overall relapse rate of 1.69%. The relapse rate was significantly higher in the immunologically unstable N?L (Borderline) cases (2.9%). It was also higher in those who had dapsone monotherapy (1.92%) compared to those who had multidrug therapy (1.01%). The relapse rate was higher in the 10 to 29 years age group and among those who became pregnant suggesting puberty and pregnancy could be risk factors. Males had a significantly higher relapse rate (2.1%) than females (1.1%). 45.2% of relapses in N (Non-lepromatous) cases occurred within 24 months and 71.4% within 36 months of stopping treatment. In those having monotherapy, 57.1% of relapses occurred within 24 months and 76.8% within 36 months. Regularity in treatment did not seem to have much influence on relapse rates.

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