02083nas a2200313 4500000000100000008004100001260001300042653001000055653000900065653002100074653001100095653001100106653001200117653002400129653002500153653002500178653002200203653000900225653001600234653001700250100002300267700002000290700002000310245007100330300001100401490000700412520133600419022001401755 1992 d c1992 Jun10aAdult10aAged10aCoronary Disease10aFemale10aHumans10aleprosy10aLeprosy, Borderline10aLeprosy, lepromatous10aLeprosy, Tuberculoid10aLipoproteins, HDL10aMale10aMiddle Aged10aRisk Factors1 aDiamantopoulos E J1 aAnthopoulos L P1 aMoulopoulos S D00aCoronary heart disease risk factors in Hansen's disease sufferers. a436-400 v153 a
In the frame of an epidemiologic study of Hansen's disease (HD) sufferers, several risk factors have been investigated which might explain the high prevalence of coronary heart disease (CHD) among HD patients. The data analyzed in the present study are derived from 293 HD patients (157 men and 136 women). The patients, after having completed a WHO adopted questionnaire, were given a complete physical examination, a resting and an exercise electrocardiogram, and biochemical as well as hematological examinations. Coronary HD patients, when compared to noncoronary HD patients, showed statistically significant differences in the following parameters: (1) mean age, (2) mean concentration of the electrophoretic fraction of alpha-lipoproteins, (3) deviation from mean weight, (4) prevalence of hypertension, and (5) prevalence of the borderline lepromatous form of HD. However, the differences found when comparing other parameters, such as blood pressure, smoking, diabetes mellitus, total cholesterol, triglycerides, pre-beta and beta-lipoproteins, uric acid, erythrocyte sedimentation rate, ABO blood groups, etc., did not reach the level of significance. These findings suggest that HD sufferers are a special population subgroup with reference to CHD risk factors, differing in many ways from the general population.
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