01536nas a2200421 4500000000100000008004100001260001300042653001000055653002600065653002600091653001600117653002100133653001200154653002600166653003000192653001100222653001100233653002900244653002000273653002300293653001200316653002300328653001300351653002800364653004400392100002300436700001400459700001200473700001500485700001800500700002000518700001600538245006300554300001000617490000700627520046600634022001401100 2005 d c2005 Oct10aAdult10aAnti-Bacterial Agents10aAntitubercular Agents10aClofazimine10aCyclophosphamide10aDapsone10aDrug Hypersensitivity10aDrug Therapy, Combination10aFemale10aHumans10aImmunosuppressive Agents10aKidney Diseases10aLeprostatic Agents10aleprosy10aMethylprednisolone10aRifampin10aTuberculosis, Pulmonary10aVasculitis, Leukocytoclastic, Cutaneous1 aAlves-Rodrigues EN1 aRibeiro L1 aSilva M1 aTakiuchi A1 aRabel-Filho O1 aMartini-Filho D1 aFontes CJ F00aRenal hypersensitivity vasculitis associated with dapsone. ae51-30 v463 a

We describe clinical and pathological features of kidney and skin involvement in a patient with hypersensitivity vasculitis associated with dapsone. Although visceral damage occurs rarely, similar skin and kidney histopathologic and immunohistochemical findings indicate that this organ is a target for type IV cell-mediated dapsone reaction. To our knowledge, this is the first reported case of renal hypersensitivity vasculitis associated with dapsone.

 a1523-6838