02038nas a2200589 4500000000100000008004100001260001300042653001200055653002500067653002400092653002300116653002300139653001400162653002000176653001600196653003100212653001600243653001100259653002300270653002100293653002300314653001200337653001600349653002700365653002200392653002600414653003600440653002700476653002500503653002600528653002800554653001800582653002400600653003100624100001300655700001300668700001500681700001600696700001200712700001500724700001200739700001300751700001000764700001400774700001200788700001500800245005500815300000900870490000700879520054800886022001401434 2005 d c2005 Feb10aAnimals10aAntigen Presentation10aAntigens, Bacterial10aBacterial Proteins10aBacterial Vaccines10aCytokines10aDendritic Cells10aDrug Design10aDrug Resistance, Bacterial10aGlycolipids10aHumans10aImmunity, Cellular10aImmunity, Innate10aLeprostatic Agents10aleprosy10aMacrophages10aMembrane Glycoproteins10aMembrane Proteins10aMinisatellite Repeats10aMolecular Diagnostic Techniques10aMolecular Epidemiology10aMycobacterium leprae10aPolymorphism, Genetic10aReceptors, Cell Surface10aSchwann Cells10aToll-Like Receptors10aTranscriptional Activation1 aMakino M1 aSuzuki K1 aFukutomi Y1 aYamashita Y1 aMaeda Y1 aMiyamoto Y1 aMukai T1 aNakata N1 aKai M1 aYmazaki T1 aGidoh M1 aMatsuoka M00a[Current advances in leprosy research activities]. a3-220 v743 a

Due to the advent of multi-drug therapy (MDT) recommended by the WHO, for the treatment of leprosy, presently, leprosy is regarded as a "curable disease". The number of new cases in Japan is relatively very low, due to which the disease is likely to be neglected, but on scientific grounds, there is a necessity to perform in depth studies. Leprosy caused by M. leprae is still unclear on various aspects including transmission, immunology, nerve damage etc. Here we introduce the recent advances in the field of basic leprosy research.

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