02349nas a2200397   4500000000100000008004100001260001300042653001500055653001000070653001600080653002500096653002500121653001100146653001100157653001000168653001200178653000900190653002000199653001600219653002600235653001600261653002100277653001800298100001300316700001400329700001300343700001600356700001100372245008400383856005100467300001000518490000700528050003200535520137000567022001401937       2005                            d  c2005 Mar10aAdolescent10aAdult10aAge Factors10aCase-Control Studies10aContrast Sensitivity10aFemale10aHumans10aIndia10aleprosy10aMale10aMedical Records10aMiddle Aged10aRetrospective Studies10aSex Factors10aVision Disorders10aVisual Acuity1 aDaniel E1 aAppavoo R1 aChacko S1 aRagupathy A1 aRaju R00aImpaired contrast sensitivity among leprosy patients with normal visual acuity.  uhttps://leprosyreview.org/article/76/1/05-5064  a55-640 v76  aInfolep Library - available3 a<p>Contrast sensitivity is a person's ability to identify an object from its background. Patients with normal visual acuity can have reduced contrast sensitivity and may experience trouble in identifying objects at night or moving around in dimly lit places. Contrast sensitivity has never been studied in leprosy patients having normal visual acuity. This study aimed to determine if contrast sensitivity is impaired in leprosy patients who have normal visual acuity and to identify possible associations with demographic, leprosy and ocular characteristics. A hospital based study measuring and comparing contrast sensitivity using the VCT 6500 chart in 127 consecutive leprosy patients without clinically apparent ocular complications and 123 non-leprosy controls was done. Contrast sensitivity was impaired in leprosy patients in all five spatial frequencies (1.5, 3.0, 6.0, 12 and 18 cycles/degree) investigated. Among leprosy patients, contrast sensitivity falling outside the normative range was associated with increasing age (adjusted OR 1.28, 95% CI: 1.14-1.42), being female (adjusted OR 11.05, 95% CI: 2.93-41.69) and having a grade 2 deformity (adjusted OR 6.43, 95% CI:1.68-24.61). Contrast sensitivity is impaired in leprosy patients having normal visual acuity. Elderly, deformed, female patients are particularly burdened with this vision loss.</p>  a0305-7518