01493nas a2200349   4500000000100000008004100001260001300042653001500055653001000070653000900080653001000089653003300099653003000132653001100162653001100173653002300184653001200207653000900219653001600228653002200244100001200266700001500278700001800293700001400311700001200325245010500337856004100442300001000483490000700493520062900500022001401129       2004                            d  c2004 Sep10aAdolescent10aAdult10aAged10aChild10aDrug Administration Schedule10aDrug Therapy, Combination10aFemale10aHumans10aLeprostatic Agents10aleprosy10aMale10aMiddle Aged10aTreatment Outcome1 aSales A1 aSabroza PC1 aCosta Nery JA1 aDuppre NC1 aSarno E00aA comparative study between 12 and 24-dose therapeutic regimens for multibacillary leprosy patients.  uhttp://ila.ilsl.br/pdfs/v72n3a09.pdf  a320-30 v723 a<p>A comparative study was made of the initial and final bacterial indices (BIs) of 213 MB leprosy patients who had been administered 12-dose (Group 1/128 patients) and 24-dose (Group 2/85 patients) World Health Organization multi-drug therapy to measure the effectiveness of both treatment regimens. All patients were evaluated at the beginning of treatment, at 12 months, and again after 24 months had elapsed. Decline in BI values and average BIs at 24 months were found to be similar for both groups. Moreover, no statistical difference between the two treatment regimens was found in the frequency rate of reaction.</p>  a0148-916X