01498nas a2200277   4500000000100000008004100001260001700042653001500059653001100074653001200085653001900097653001500116653000900131653002800140100001500168700001800183700001200201700001500213700001700228245009400245300000900339490000700348050003200355520081900387022001401206       2004                            d  c2004 Jan-Mar10aCell Count10aHumans10aleprosy10aLupus Vulgaris10aMast Cells10aSkin10aTuberculosis, Cutaneous1 aBagwan I N1 aKhandekar M M1 aKadam P1 aJadhav M V1 aDeshmukh S D00aA study of mast cells in granulomatous lesions of skin, with special emphasis on leprosy.  a31-70 v76  aInfolep Library - available3 a<p>76 skin biopsies that included material from 7 controls, 65 granulomatous skin lesions and 2 each of granulation tissue and chronic non-specific inflammation, were subjected to histopathological evaluation on haematoxylin and eosin and pertinent special stains. Mast cell study was done on slides stained by toluidine blue method, with special reference to their location, and morphology and cell count were done with the help of occculomicrometre. In normal skin, mast cell density was 11.43/mm2 with a range of 6-22/mm2 and an S.D. of 5.94. Highest value in the whole series was seen in TVC (66/mm2), followed by lupus vulgaris (50/mm2). Mast cell counts were normal in indeterminate and TT leprosy and showed a rise over the immunological spectrum BT to LL, with values in LL being 32.86/mm2 (28-40/mm2).</p>  a0254-9395