01602nas a2200289   4500000000100000008004100001260001300042653001700055653002400072653001800096653002200114653001100136653002400147653002500171653002500196653002600221100001200247700001400259700002100273700001200294700001300306245009800319300001000417490000700427520086400434022001401298       2004                            d  c2004 Jun10aAzure Stains10aBiopsy, Fine-Needle10aCytodiagnosis10aDiagnostic Errors10aHumans10aLeprosy, Borderline10aLeprosy, lepromatous10aMycobacterium leprae10aRetrospective Studies1 aSingh N1 aManucha V1 aBhattacharya S N1 aArora V1 aBhatia A00aPitfalls in the cytological classification of borderline leprosy in the Ridley-Jopling scale.  a386-80 v303 a<p>This is a blinded, retrospective, correlative study of classification of leprosy by cytomorphology, clinical examination, and bacterial density. One hundred consecutive adequate aspirates from skin lesions of leprosy were studied. The Ridley-Jopling (R-J) five-group classification system was used. May-Gruenwald-Giemsa (MGG) and Ziehl-Neelsen (Z-N) stains were employed. Complete clinical, cytological, and bacteriological concordance was found in 88 patients. One-step mismatch in classification was seen in 12 patients with cytomorphological features of borderline-borderline (BB/mid-borderline) leprosy. Cytomorphological features of BB leprosy in aspirates from skin lesions should alert the cytopathologist to the possibility that the bacteriological index (BI) may vary widely. Appropriate steps must be taken to ensure accurate reporting of BI.</p>  a8755-1039