01723nas a2200301   4500000000100000008004100001260000900042653002400051653002600075653002400101653001600125653001100141653001000152653001200162653001700174653002500191653003200216100001600248700001600264700001200280700001100292700001600303245012500319300001100444490000700455520094500462022001401407       1992                            d  c199210aAgglutination Tests10aAntibodies, Bacterial10aAntigens, Bacterial10aGlycolipids10aHumans10aLatex10aleprosy10aMicrospheres10aMycobacterium leprae10aSensitivity and Specificity1 aVaishnavi C1 aAgnihotri N1 aKumar B1 aKaur S1 aGanguly N K00aField utility of phenolic glycolipid coated latex agglutination test for rapid detection of bacilliferous leprosy cases.  a169-730 v363 a<p>Serum samples were collected from eighty-three leprosy patients and twenty-five healthy controls supposedly not exposed to Mycobacterium leprae infection. Phenolic glycolipid-1 coated latex agglutination test (PGL-LAT) was carried out with the serum samples to detect antibodies specific to M. leprae. Samples showing positive agglutination were 50% in the lepromatous leprosy (LL) group showing no erythema nodosum leprosum (ENL) complications, 66.6% in LL group with ENL complication, 60% in borderline lepromatous (BL) group, 50% in borderline (BB) and 33.3% in borderline tuberculoid (BT). The patients belonging to the tuberculoid (TT) group and most of the long-term treated patients were interestingly negative, and so were sera from all the healthy controls. PGL-LAT developed by us therefore is specific and a fairly sensitive technique to detect antibodies specific to M. leprae and will be very useful in field conditions.</p>  a0022-1732