01530nas a2200349   4500000000100000008004100001260001300042653001500055653001000070653002300080653002100103653001100124653001100135653002400146653002500170653000900195653001600204653003000220653001800250653002400268653002400292100001500316700002100331700001100352700001500363700001400378245008300392300001000475490000700485520067400492022001401166       1992                            d  c1992 Sep10aAdolescent10aAdult10aC-Reactive Protein10aErythema Nodosum10aFemale10aHumans10aLeprosy, Borderline10aLeprosy, lepromatous10aMale10aMiddle Aged10aPredictive Value of Tests10aReaction Time10aRemission Induction10aAlpha 1-Antitrypsin1 aSehgal V N1 aBhattacharya S N1 aShah Y1 aSharma V K1 aGupta C K00aReaction in leprosy: acute phase reactant response during and after remission.  a632-40 v313 a<p>Sera from 25 patients with type 1 (Lepra), upgrading and downgrading, and type 2 (erythema nodosum leprosum [ENL]) reactions were assayed, during the reaction and after its clinical remission, for changes in levels of alpha-1-antitrypsin (A1A) and C-reactive protein (CRP). The results were compared with those from normal healthy adults and patients of leprosy without history and/or clinical evidence of reaction. The A1A levels correlated better with changes in status of type 1 reaction; whereas CRP levels correlated well with alterations in type 2 reactions and were definitely superior to A1A in this situation for monitoring the course of these episodes.</p>  a0011-9059