01539nas a2200325   4500000000100000008004100001260001300042653000900055653001200064653003000076653003100106653001100137653001000148653002300158653001200181653000900193653001700202653002200219100001300241700001600254700001300270700001300283700001200296700001500308245004000323300001100363490000700374520081800381022001401199       2003                            d  c2003 Aug10aAged10aBolivia10aDrug Therapy, Combination10aEmigration and Immigration10aHumans10aJapan10aLeprostatic Agents10aleprosy10aMale10aPrednisolone10aTreatment Outcome1 aSugita Y1 aYoshinaka M1 aMukawa R1 aOonuma S1 aIshii N1 aNakajima H00a[A case of multibacillary leprosy].  a279-810 v723 a<p>We report a 74-year-old Japanese man who occurred leprosy at the age of 68. He moved to Bolivia at the age of 33 as an immigrant. He complained erythematous plaques on his trunk and extremeties and dysuria. Skin biopsy specimen revealed granulomatous lesions and acid fast staining showed numerous number of positively stained bacilli. He was diagnosed as multibacillary leprosy and MDT containing DDS, RFP, and CLF was started. During the treatment, he developed borderline reaction twice presenting severe pain and marked swelling on his hand and foot. The reaction was successfully treated with daily dose of 50 mg prednisolone combined with anti-leprosy drugs. SPFX, MINO, and CAM were not able to be used due to the side effects. One year has been passed after the stop of treatment without relapse.</p>
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