01171nas a2200217   4500000000100000008004100001260001300042653001200055653001100067653001200078653001700090100001600107700001600123700001500139245014000154856004100294300001000335490000700345520058700352022001400939       1983                            d  c1983 Sep10aDapsone10aHumans10aleprosy10aTime Factors1 aAlmeida J G1 aChristian M1 aChacko C J00aResponse to dapsone (DDS) monotherapy in leprosy patients of Gudiyatham Taluk, South India: comparison between the 1960s and the 1970s.  uhttp://ila.ilsl.br/pdfs/v51n3a12.pdf  a378-80 v513 a<p>At the Schieffelin Leprosy Research and Training Centre, Karagiri, India, 148 lepromatous (LL) and borderline lepromatous (BL) leprosy patients registered for treatment in the years 1971 to 1973 were found to respond as well to dapsone (DDS) monotherapy as 391 LL and BL patients registered in 1964 to 1966, as indicated by clearance of Mycobacterium leprae from skin smears during the initial seven years of therapy in each patient. Apparently, the efficacy of DDS monotherapy has not been progressively diminishing since the introduction of DDS monotherapy into the area.</p>
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