01496nas a2200241   4500000000100000008004100001260000900042653001200051653001300063653001100076653003100087653001100118653001200129653001100141653001300152100001400165245018000179856008300359300001100442490000700453520078000460022001401240       1962                            d  c196210aAnimals10aBacillus10aCattle10aComplement System Proteins10aHumans10aleprosy10aLipids10aSyphilis1 aALMEIDA J00aSerological studies on leprosy. A comparison of complement-fixation tests using antigens prepared from tubercle bacilli and beef-heart lipids with other serological reactions.  uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2555671/pdf/bullwho00312-0087.pdf  a233-400 v263 a<p>Sera from lepromatous leprosy patients were subjected to a battery of serological tests, including flocculation, agglutination and complement fixation. A correlation was found between the antileprous antibody content and the reactivity with "cardchol" antigen, but not with Trypanosoma cruzi antigen, cardiolipin or Rubino antigen. The reactivity of leprous sera with tubercle bacilli antigen in the quantitative complement-fixation test decreased in three patients with lepromatous leprosy during sulfone treatment. When syphilis was present in a lepromatous leprosy case, it was possible to follow the effect of specific treatment of the two infections, with sulfone and with penicillin, by the drawing of two serological curves-one for leprosy and one for syphilis.</p>  a0042-9686