01191nas a2200277   4500000000100000008004100001260001700042653001200059653002700071653001100098653001200109653001000121653000900131653002400140653002300164653002500187653001100212100002000223700001500243245004800258300001100306490000700317050003200324520054300356022001400899       1992                            d  c1992 Oct-Dec10aAnimals10aDisease Models, Animal10aFemale10aleprosy10aLiver10aMice10aMice, Inbred BALB C10aMice, Inbred C57BL10aMycobacterium leprae10aSpleen1 aGangadharam P R1 aDhople A M00aUtility of beige mouse in leprosy research.  a475-810 v64  aInfolep Library - available3 a<p>Dissemination of M. leprae to visceral organs is seen by four months onwards only in beige (C57BL/6/bgj) but not BALB/c mice following intravenous or intraperitoneal infections. Inoculation of the beige mouse derived M. leprae showed all the characteristics of M. leprae, including growth pattern in the foot-pads of BALB/c mice. M. leprae inoculated into foot-pads of beige mice multiplied faster than those in the foot-pads of BALB/c mice. The possibility of using beige mouse in chemotherapeutic studies in leprosy is discussed.</p>  a0254-9395