01035nas a2200253 4500000000100000008004100001260001300042653003700055653001000092653001900102653001700121653001100138653001200149653001900161653001400180653001400194653001800208100001300226245004100239300000800280490000700288520047200295022001400767 1983 d c1983 Jan10aAsian Continental Ancestry Group10aChina10aDrug Eruptions10aHLA Antigens10aHumans10aleprosy10aLupus Vulgaris10aPsoriasis10aSingapore10aSkin Diseases1 aChan S H00aHLA and skin disease in the Chinese. a3-50 v123 a

The HLA associations in skin diseases among the Chinese were reviewed. Tuberculoid leprosy was associated with B17 (RR = 4.1). This HLA association was reinforced in the finding of excess HLA haplotype sharing among affected siblings in multiple case families. In psoriasis the associations were with A1, AW30 and B13. The relative risk associated with AW30, B13 was 16.1. In SLE, mild patients were associated with B13 (RR = 3.7) and severe patients with B17.

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