01571nas a2200301   4500000000100000008004100001260001700042653002800059653002600087653001800113653002100131653001800152653001100170653002500181653000900206653001600215653003500231100001400266700001500280700001900295700001200314245004200326300001000368490000700378050003200385520083800417022001401255       2002                            d  c2002 Apr-Jun10aAdrenal Cortex Hormones10aAnti-Infective Agents10aCiprofloxacin10aErythema Nodosum10aFatal Outcome10aHumans10aLeprosy, lepromatous10aMale10aMiddle Aged10aSkin Diseases, Vesiculobullous1 aDavis S V1 aShenoi S D1 aBalachandran C1 aPai S B00aA fatal case of erythema necroticans.  a145-90 v74  aInfolep Library - available3 a<p>Erythema nodosum leprosum (ENL) classically presents as tender, erythematous nodules over the face, arms and legs. Severe ENL can become vesicular or bullous and break-down and is termed erythema necroticans (Jopling & McDougall, 1996) and is treated with corticosteroids. The causes of death in a majority of leprosy patients are the same as in the general population, with the exception of renal damage in lepromatous leprosy. There is possible increased mortality from side-effects of antileprosy drugs, steroids, or other drugs used in reactions, from toxaemia in severe reactions, and from asphyxia due to glottic oedema (Jopling & McDougall, 1996). We report here a case of erythema necroticans, the cause of death being septicaemia, secondary to skin ulcers and urinary tract infection, precipitated by corticosteroids.</p>  a0254-9395