01165nas a2200133 4500000000100000008004100001100001500042245007400057856007600131300001000207490000600217520079400223022001401017 2012 d1 aWorobec SM00aCurrent approaches and future directions in the treatment of leprosy. uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6067781/pdf/rrtm-3-079.pdf a79-910 v33 a

This review surveys current treatments and future treatment trends in leprosy from a clinical perspective. The World Health Organization provides a multidrug treatment regimen that targets the bacillus which causes leprosy. Several investigational drugs are available for the treatment of drug-resistant . Future directions in leprosy treatment will focus on: the molecular signaling mechanism uses to avoid triggering an immune response; prospective studies of the side effects experienced during multiple-drug therapy; recognition of relapse rates post-completion of designated treatments; combating multidrug resistance; vaccine development; development of new diagnostic tests; and the implications of the recent discovery of a genetically distinct leprosy-causing bacillus, .

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