01383nas a2200145 4500000000100000008004100001100001900042700001200061700001300073700001800086700001300104245011400117520099200231022001401223 2018 d1 aPanduranga M S1 aVibha D1 aPrasad K1 aSrivastava AK1 aShukla G00aClinical spectrum and quality of life (QoL) in patients with chronic polyneuropathy: A cross-sectional study.3 a

Chronic polyneuropathy is a disabling condition of the peripheral nerves, characterized by symmetrical sensory motor symptoms and signs. There is paucity of studies on the etiological spectrum of polyneuropathy and its impact on quality of life. The present cross sectional study in a referral based tertiary care center in North India found diabetic neuropathy as the commonest cause (25.5%) amongst 212 patients with chronic polyneuropathy. Idiopathic axonal polyneuropathy was present in 14.2% patients. Leprosy presenting as confluent mononeuritis multiplex constituted 11.3 % of the patients. Additionally, it revealed a significantly worse quality of life in these patients in all domains measured by short form (SF-36). This is the first study conducted in India to determine the quality of life in chronic neuropathy patients. The current study demonstrates the clinical feasibility and applicability of the SF-36 generic health status in patients with polyneuropathies.

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