01418nas a2200313   4500000000100000008004100001260001700042653001500059653001000074653000900084653001200093653001000105653001100115653001100126653001300137653001200150653000900162653001600171653001500187653001400202100001500216700001400231700001600245245007300261300001100334490000700345520073800352022001401090       1975                            d  c1975 Jul-Sep10aAdolescent10aAdult10aAged10aAnimals10aChild10aFemale10aHumans10aLepromin10aleprosy10aMale10aMiddle Aged10aSkin Tests10aXenarthra1 aMeyers W M1 aKvernes S1 aBinford C H00aComparison of reactions to human and armadillo lepromins in leprosy.  a218-250 v433 a<p>To assess the usefulness of Mycobacterium leprae-infected armadillo tissue as a substitute for human lepromas for the manufacture of lepromin, we compared skin reactions to preparations from these two sources in 115 leprosy patients. The patient sample represented all the primary clinical forms of leprosy. Lepromin derived from the armadillo (lepromin-A) provoked the same pattern of responses as human derived lepromin (lepromin-H), i.e., lepromatous patients gave the weakest reactions. Lepromin-A reactions were consistently more intense than those to lepromin-H. We conclude that lepromin-A is a promising alternative to lepromin-H and may make the worldwide distribution of a standardized skin testing reagent feasible.</p>  a0148-916X