01088nas a2200277 4500000000100000008004100001260001700042653002600059653001800085653001800103653001800121653003100139653002100170653001100191653001200202653000900214653001600223653001900239100001400258700001400272245010700286300001000393490000700403520038600410022001400796 1975 d c1975 Jul-Sep10aArthritis, Infectious10aComplement C110aComplement C210aComplement C410aComplement System Proteins10aErythema Nodosum10aHumans10aleprosy10aMale10aMiddle Aged10aSynovial Fluid1 aLouie J S1 aGlovsky M00aComplement determinations in the synovial fluid and serum of a patient with Erythema nodosum leprosum. a252-50 v433 a

Simultaneous serum and synovial fluid CH50, C1, C4, C2, C1 esterase inhibitor and C3 protein were determined in a patient with acute erythema nodosum leprosum. The pattern of synovial fluid complement activity coupled with the demonstration of multiple lepra bacilli free and within histiocytes is more consistent with an infectious than an immune complex induced synovitis.

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