01563nas a2200301 4500000000100000008004100001260001700042653001000059653002900069653001100098653002300109653001000132653001000142653001500152653001300167653001200180653001300192653001500205100002000220700001500240700001200255245003100267856004100298300001000339490000700349520089100356022001401247 1975 d c1975 Oct-Dec10aChina10aFalse Positive Reactions10aHumans10aImmunity, Cellular10aIndia10aJapan10aKveim Test10aLepromin10aleprosy10aMalaysia10aSkin Tests1 aKrishnamurthy S1 aVerghese R1 aJob C K00aThe Kveim test in leprosy. uhttp://ila.ilsl.br/pdfs/v43n4a06.pdf a333-80 v433 a
The response to lepromin and Kveim antigens was compared and studied in 15 leprosy patients who were tuberculin negative. Of the 11 lepromin positive tuberculoid patients, 4 were Kveim positive, 1 was equivocal, and the rest were negative. Of the four lepromin negative lepromatous patients, one gave a positive Kveim test while the other three were negative. It has been shown that false-positive Kveim reactions are found in a higher percentage of South Indian leprosy patients than in those of other backgrounds, such as Japanese and Malaysian Chinese patients. It is also suggested that no definite relationship exists between the reaction of leprosy patients to lepromin and Kveim antigens. We further suggest that the anergy exhibited by lepromatous patients to the antigen of M. leprae is specific, as evidenced by the positive Kveim response in one lepromatous patient.
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