02505nas a2200313   4500000000100000008004100001653001600042653003900058653002700097653001600124653000900140653001200149653001100161653001100172653002200183653001000205100001400215700001400229700001700243700001400260700001900274700001400293245010600307856005100413300001000464490000700474520169600481022001402177       2016                            d10aYoung Adult10aPeripheral Nervous System Diseases10aNeurologic Examination10aMiddle Aged10aMale10aleprosy10aHumans10aFemale10aElectrophysiology10aAdult1 aLima PODP1 aCunha FMB1 aGonçalves H1 aAires MAP1 aDe Almeida RLF1 aKerr LRFS00aCorrelation between clinical tests and electroneuromyography for the diagnosis of leprosy neuropathy.  uhttps://leprosyreview.org/article/87/1/06-0070  a60-700 v873 a<p><strong>BACKGROUND: </strong>In leprosy, sensory function of nerves is evaluated with monofilaments test and the motor function with voluntary muscle test, however electroneuromyography is considered as the gold-standard tool.</p>

<p><strong>OBJECTIVES: </strong>This study aimed: i) to evaluate the correlation between clinical tests and electroneuromyography for the diagnosis of leprosy neuropathy; and ii) to identify the prevalence of leprosy neuropathy and the most compromised peripheral nerves in leprosy.</p>

<p><strong>METHODS: </strong>We analysed the data from a nested case-control study that identified 166 patients diagnosed with leprosy neuropathy confirmed by electromyography. This study was designed for an analysis of correlation between the diagnostic tests.</p>

<p><strong>RESULTS: </strong>The most prevalent type of the neural damage was the sensory and motor multiple mononeuropathy, observed in 62 (37.3%) cases. The highest prevalence was the ulnar nerve in 67 (40.3%) cases. Agreement specified by nerves was moderate, ranging from k = 0.58 in the deep peroneal nerve to k = 0.41 in the posterior tibial nerve). Overall agreement between the clinical tests and electroneuromyography was very poor. Monofilaments test with k = 0.02 (95% CI 0.00-0.12) and voluntary muscle test with 0.16 (95% CI 0.04 to 0.28, P = 0.01).</p>

<p><strong>CONCLUSIONS: </strong>There is a low to moderate correlation between clinical tests (monofilaments and voluntary muscle tests) and the electroneuromyography examination. The most prevalent type of neural impairment was the sensory and motor multiple mononeuropathy, and the most affected nerve was the ulnar.</p>
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