01525nas a2200217 4500000000100000008004100001653001600042653001200058653001900070653001400089100001400103700001400117700001200131700001500143700001100158245005900169856003300228300001200261490000600273520102800279 2017 d10aTuberculoid10aleprosy10aHistopathology10aGranuloma1 aGhodke BA1 aValand AG1 aDeka AB1 aRamraje SN1 aAli ZS00aClinico histopathological correlation study of leprosy uhttps://tinyurl.com/ya7pa8cv a788-7940 v43 a

Background: Aim of the study was to study the histomorphological changes in leprosy, the clinicopathological correlation of different types of leprosy lesions and cases of clinically diagnosed lepra reaction.

Methods: One hundred and twelve patients of clinically diagnosed leprosy were chosen. Skin biopsy was performed, fixed in 10% buffered formalin, processed, sectioned and stained with Hematoxylin and Eosin as well as Modified Fite Faraco stain.

Result: Of the one hundred and twelve patients enrolled in the study (age range from 7 to 70 years) 90 patients were males and 22 were females. All cases were classified according to the Ridley Jopling Scale. Correlation between clinical diagnosis and histopathological type of leprosy and lepra reactions was done.

Conclusion: Leprosy is more common in males than in females having a ratio of 4:1.The commonest histopathological subgroup was tuberculoid leprosy.