01958nas a2200205   4500000000100000008004100001653003900042653002300081653001900104653001100123100001500134700001300149700001400162245010700176856003300283300000700316490000900323520140600332022001401738       2018                            d10aNeglected tropical diseases (NTDs)10aMathematical model10aDengue control10aDengue1 aBustamam A1 aAldila D1 aYuwanda A00aUnderstanding dengue control for short- and long-term intervention with a mathematical model approach.  uhttps://tinyurl.com/ydgxjj4w  a130 v20183 a<p>A mathematical model of dengue diseases transmission will be discussed in this paper. Various interventions, such as vaccination of adults and newborns, the use of insecticides or fumigation, and also the enforcement of mechanical controls, will be considered when analyzing the best intervention for controlling the spread of dengue. Frommodel analysis, we find three types of equilibrium points which will be built upon the dengue model. In this paper, these points are the mosquito-free equilibrium, disease-free equilibrium (with and without vaccinated compartment), and endemic equilibrium. Basic reproduction number as an endemic indicator has been found analytically. Based on analytical and numerical analysis, insecticide treatment, adult vaccine, and enforcement ofmechanical control are themost significant interventions in reducing the spread of dengue disease infection caused by mosquitoes rather than larvicide treatment and vaccination of newborns. From short- and long-term simulation, we find that insecticide treatment is the best strategy to control dengue. We also find that, with periodic intervention, the result is not much significantly different with constant intervention based on reduced number of the infected human population. Therefore, with budget limitations, periodic intervention of insecticide strategy is a good alternative to reduce the spread of dengue.</p>
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