01488nas a2200217   4500000000100000008004100001653001200042653001500054653001800069653001600087653001600103100001300119700001400132700001400146245005600160856007200216300001400288490000600302520094900308022001301257       2017                            d10aleprosy10aMast Cells10aMetachromatic10aLepromatous10aTuberculoid1 aJindal S1 aManjari M1 aGirdhar M00aRole of mast cells in leprosy- A study of 62 cases.  uhttps://www.jemds.com/data_pdf/shivani%20jindal-%20--sept%2018-.pdf  a5328-53310 v63 a<p><strong>BACKGROUND</strong></p>

<p>Mast cells have received little attention in leprosy, but evidence linking them with delayed-type hypersensitivity reactions raises the possibility that they may be of some importance in leprosy.</p>

<p><strong>MATERIALS AND METHODS</strong></p>

<p>The present study is a descriptive study. Biopsies obtained from the clinically diagnosed patients were fixed in 10% formalin, processed and three sections of 6 µm thickness were cut and stained with routine Haematoxylin and Eosin (Culling, Allison, Barr 1985), by Toluidine Blue and by Modified Thionin/Acridine Orange method.</p>

<p><strong>RESULTS</strong></p>

<p>Mean number of mast cells were more in lepromatous leprosy than in tuberculoid.</p>

<p><strong>CONCLUSION</strong></p>

<p>This study reflects the variety of immunological reactions occurring in leprosy and the role of mast cells in these immunological phenomena.</p>
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