01256nas a2200241   4500000000100000008004100001653001200042653003100054653003500085653002600120653001500146100001100161700001300172700001200185700001300197700001500210245011200225856003300337300001200370490000600382520061200388022001401000       2018                            d10aleprosy10aGuillain–Barré syndrome10aBorderline tuberculoid leprosy10aType 1 lepra reaction10aNeuropathy1 aDash D1 aSaluja A1 aSingh R1 aBhatia R1 aTripathi M00aGuillain–Barre syndrome: A rare presentation of borderline tuberculoid leprosy with Type 1 lepra reaction  uhttps://tinyurl.com/ydxb8n4o  a423-4250 v93 a<p>Guillain–Barre syndrome (GBS) is an autoimmune polyradiculoneuropathy usually preceded by respiratory tract or gastrointestinal infection. The pathogenesis in GBS is based on molecular mimicry mechanism. Hansen's disease is common in India and is the most common infectious cause of neuropathy. We describe a 42-year-old man who was being treated for borderline tuberculoid leprosy and developed Type 1 lepra reaction followed by GBS and responded to plasmapheresis. Lepra reaction may lead to exposure of neural antigens, resulting in autoimmune mechanism and demyelination of peripheral nerves.</p>
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