01113nas a2200133   4500000000100000008004100001100001400042700001400056245005000070856007100120300001200191490000700203520076900210       2016                            d1 aRambhia K1 aKhopkar U00aElastophagocytosis and Elastolysis in Leprosy  uhttp://www.ijl.org.in/2016/7%20KD%20Rambhia%20et%20al(129-131).pdf  a129-1310 v883 a<p>Elastophagocytosis is the engulfment of the elastic fibres by the histiocytes, multinucleated giant cells, or both. The cutaneous lesions showing elastophagocytosis are annular elastolytic giant cell granuloma, actinic keratoses, persistent insect-bite reactions, elastosis perforans serpiginosa, foreign body granuloma. Occasionally, it may occur in infectious diseases like leprosy, granulomatous syphilis, North-American blastomycosis, bacterial folliculitis, and cutaneous leishmaniasis. We report a case of lepromatous leprosy with necrotic erythema nodosum leprosum with secondary anetoderma. Histopathology from the atrophic macule of anetoderma revealed periappendageal, perineural infiltration, elastophagocytosis and reduction in elastic fibres.</p>