01273nas a2200205   4500000000100000008004100001653001200042653001300054653002300067653001500090653002500105653002500130653000800155100001300163245009000176856010300266300001000369490001100379520067700390       2016                            d10aleprosy10aLEPRASIM10ainfectious disease10aGeoscience10aBacterial Infections10aAgent-based-modeling10aABM1 aHoek S A00aLEPRASIM: An Agent-based model for the spatio-temporal diffusion dynamics of leprosy.  uhttp://dspace.library.uu.nl/bitstream/handle/1874/342409/Thesis_vanderHoek_s6020453.pdf?sequence=2  a1-1260 vMaster3 a<p>LEPRASIM, an Agent Based Model, is developed to gain a deeper understanding of the spatio-temporal diffusion dynamics of leprosy infections, the effect of agent-based behavioral mechanisms on this phenomenon, and the long-term effectiveness of prevention measures in reducing the occurrence of leprosy in a population. A set of eight prevention measures are tested aimed at different contact groups of infected individuals in the population. Of these strategies an initial deployment of a "blanket"-approach, followed by the deployment of a pre-emptive approach aimed at household and neighbor contacts of infected individuals, is considered to be most effective.</p>